Saffron for rapid treatment of depression and anxiety
Author : Hamed Biglari | 2024 Jan 04

Saffron For Rapid Treatment Of Depression And Anxiety

Over decades, studies have continued to lighten the potential use of Saffron, a mysterious spice, for treating depression. In a quality review research published in Molecules, a prestigious international journal, Antidepressant Properties of Crocin Molecules in Saffron (Crocus sativus L.) by Shahida Anusha Siddiqui et al. in 2022 has been shown to have both antidepressant and antianxiety effects. It's also antioxidant.

Saffron's Crocin molecules have been found to possess antidepressant properties and can benefit mental health. Studies have shown that consuming Saffron can help alleviate symptoms of depression and boost mood. The unique chemical composition of Crocin molecules in Saffron is responsible for its therapeutic effects. These findings have led to increased interest in exploring the potential of Saffron and its active compounds for the development of new treatments for depression and other mental health conditions. In their conclusion, the authors stated, "Crocin has been demonstrated to act as a monoamine oxidase type A and B inhibitor." So, Saffron appears to have a significant impact on the treatment of anxiety and depression disorder. Side effects were rare.

What are the potential side effects of consuming Saffron forantidepressantt effects?

Furthermore, Saffron petal extracts have experimentally been shown to impact contractile response in electrical field stimulation. Other research suggests that saffron inhibits the reuptake of monoamines, exhibits N-Methyl-D-aspartate antagonism, and improves brain-derived neurotrophic factor signaling. A host of experimental studies found Saffron/Crocin to be similarly effective as fluoxetine and imipramine in the treatment of depression disorders. Saffron and Crocin propose a natural solution to combat depressive disorders. However, some hurdles, such as stability and delivery, must be overcome.

What is the most effective way to stabilize and deliver Crocin molecules for therapeutic use?


Hamed Biglari

Assistant Professor of Environmental Health Engineering in Gonabad University of Medical Sciences, Razavi Khorasan, Iran

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